Chlorhexidine Gluconate 2% w/v in 70% v/v Isopropyl Alcohol
ACTIONS AND CLINICAL PHARMACOLOGY
Chlorhexidine is a bactericidal antiseptic effective against a large range of vegetative gram positive and gram negative bacteria, but it is more effective against gram positive bacteria. Some species of Pseudomonas and Proteus are relatively less susceptible. Chlorhexidine is ineffective against acidfast bacteria, bacterial spores, fungi and viruses.
As a cationic material, chlorhexidine is incompatible with soaps and other anionic materials.
At a concentration of 2%, chlorhexidine is incompatible with borates, bicarbonates, carbonates, chlorides, citrates, phosphates and sulfates, forming salts of low solubility, which may precipitate from solutions after standing.
Chlorhexidine is most active at a neutral pH; its activity is reduced by organic matter (blood, serum, etc.) and by phospholipids.
INDICATIONS AND CLINICAL USE
BAXEDIN 2% - 70% is indicated:
• As a cutaneous preoperative antiseptic;
• As a cutaneous antiseptic for catheter site care.
BAXEDIN 2% - 70% tinted contains a coloring agent to help identify the disinfected area.
CONTRAINDICATIONS Patients who have previously experienced a hypersensitivity to chlorhexidine (such reactions are extremely rare).